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November 16, 2012

What's your Medical Diagnosis: Abdominal Pain, Altered Mental State

The Isabel medical diagnosis tool touts an extensive database of conditions for differential diagnosis support, and we often will test its accuracy with real patient cases from the New England Journal of Medicine.

Case 2012:#24. N Engl J Med. 367(6):552-563

Demographic: Male, 38 years, Caribbean
Clinical features:

  • abdominal pain
  • altered mental status
  • hypercalcemia
  • thrombocytopenia
  • splenomegaly
  • lymphadenopathy
  • fatigue

STOP!  Before you read further you might want to construct your own final diagnosis.
In the following section you will find: The final diagnosis of the case and if Isabel suggested the final diagnosis.
Final Diagnosis of the case according to NEJM: Adult T-cell leukemia-lymphoma associated with human T-cell lymphotropic virus type 1
Was the final diagnosis given by Isabel: Yes, Adult T-cell leukemia-lymphoma in Neoplastic

Case 24 2012 resized 600

About the Isabel Diagnosis Challenge

The New England Journal of Medicine (NEJM) publishes interesting presentations of common diseases and unusual cases in the Clinical pathology Conference (CPC) series. These cases are educational and can pose diagnostic challenges even to the expert physicians at the Massachusetts General Hospital.

NEJMUsing the clinical features of these cases you can evaluate your own diagnostic skills and compare your diagnostic performance to that of the physicians at MGH. If you are registered with Isabel as a client or have a free-trial subscription, you can use the diagnosis reminder system and run through some scenarios to get a list of likely suspects. Clicking on a diagnosis will take you through to various knowledge sources and links available from within Isabel.

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